Fuller's Earth, Chromatographic

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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition

Issued and maintained by the United States Pharmacopeial Convention (USP)

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(Very Fine and Moderately Coarse)—Gray or grayish-white powder or granules consisting mainly of hydrous aluminum-magnesium silicate.

Powder Fineness: see Powder Fineness 〈811〉.

Soluble Matter: Twenty g, treated with 50 mL of cold water and filtered, yields not more than 60 mg of residue upon evaporation of the filtrate (0.3%). A second 20-g portion, treated with 50 mL of cold alcohol and filtered, yields not more than 14 mg upon evaporation of the filtrate (0.07%).

Loss on Drying 〈731〉: Dry it at 105° for 6 hours: it loses between 7.0% and 10.0% of its weight.

[Note - Adjust the water content, if necessary, by drying in vacuum at room temperature, restoring the water required, and equilibrating by shaking for 2 hours.]

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