Yeast Extract
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
-A water-soluble, peptone-like derivative of yeast cells (Saccharomyces) prepared under optimum conditions, clarified, and dried to a reddish-yellow to brown powder, having a characteristic but not putrescent odor. Soluble in water, forming a yellow to brown solution, having a slightly acid reaction. Contains no added carbohydrate.
LOSS ON DRYING (731),
Analysis: Dry at 105° to constant weight.
Acceptance criteria: NMT 6%
Residue on Ignition (Reagent test)
Analysis: Ignite 500 mg with 1 mL of sulfuric acid
Acceptance criteria: NMT 75 mg (15.0%)
Chloride (Reagent test): NMT 5% of chloride (CI), calculated as sodium chloride
Nitrogen Content (Reagent test)
Analysis: Determine by the Kjeldahl method, previously dried at 105° to constant weight.
Acceptance criteria: 7.2%-13.0% of N is found.
Microbial Content: NMT 104 cfu/g
Amino Nitrogen: 6.0%-6.9%

