Xylenol Orange
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
(N,N′-[3H-2,1-Benzoxathiol-3-ylidenebis-[(6-hydroxy-5-methyl-3,1-phenylene)methylene]]bis[N-(carboxy-methyl)glycine] S,S-dioxide),
C31H28N2Na4O13S
(salt)— 760.59,C31H28N2O13S (free acid)—672.66 (USP 1-May-2020) —Orange powder. The acid form is soluble in alcohol and the salt form is soluble in water. (USP 1-May-2020) In acid solution, it is lemon-yellow in color, and its metal complexes are intensely red. It yields a distinct endpoint where a metal such as Bismuth, cadmium, lanthanum, lead, mercury, scandium, thorium, or zinc is titrated with edetate disodium.
