Tolu Balsam Syrup

This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition

Issued and maintained by the United States Pharmacopeial Convention (USP)

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1 DEFINITION

Prepare Tolu Balsam Syrup as follows (see Pharmaceutical Compounding—Nonsterile Preparations 〈795〉).
 

Add the Tincture all at once to the Magnesium Carbonate and 60 g of the Sucrose in a mortar, and mix. Gradually add 430 mL of Purified Water with trituration, and filter. Dissolve the remainder of the Sucrose in the clear filtrate with gentle heating, strain the syrup while warm, and add sufficient Purified Water through the strainer to make the product measure 1000 mL, and mix.

Tolu Balsam Syrup may also be prepared as follows. Place 760 g of the Sucrose in a suitable percolator, the neck of which is nearly filled with loosely packed cotton, moistened after packing with a few drops of water. Pour the filtrate, obtained as directed in the preceding instructions, on the Sucrose, and regulate the outflow to a steady drip of percolate. When all of the liquid has run through, return portions of the percolate, if necessary, to dissolve all the Sucrose. Then pass enough Purified Water through the cotton to make the product measure 1000 mL, and mix.

2 OTHER COMPONENTS

ALCOHOL DETERMINATION, Method Il (611): 3.0%-5.0%

3 SPECIFIC TESTS

FATS AND FIXED OILS, Acid Value (401)

Sample solution: 2% of solution

Analysis: Add phenolphthalein TS, and titrate with 0.5 N alcoholic potassium hydroxide VS.

Acceptance criteria: 112-168

4 ADDITIONAL REQUIREMENTS

PACKAGING AND STORAGE: Package in tight containers, and store at controlled room temperature.

LABELING: The label states the Latin binomial name and, following the official name, the part of the plant source from which the article was derived.