Thrombin Human (Factor IIa)
If you find any inaccurate information, please let us know by providing your feedback here
This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
~33,600 CAS RN®: 9002-04-4.-A preparation of a serine protease (enzyme) that converts human fibrinogen into fibrin. It is obtained from human plasma and may be prepared by precipitation with suitable salts and organic solvents under controlled conditions of pH, ionic strength, and temperature. A yellowish-white powder, freely soluble in a 9 g per L solution of sodium chloride, which forms a cloudy, pale yellow solution. Store in a sealed, sterile container under nitrogen, protected from light, at a temperature below 0°. One unit corresponds to the amount of enzyme that hydrolyzes 1 µmol of Tos-Gly-Pro-Arg-4-nitroaniline acetate per minute at a pH of 8.4 and a temperature of 37°.
