Testosterone Propionate

This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition

Issued and maintained by the United States Pharmacopeial Convention (USP)

DOWNLOAD PDF HERE

Testosterone Propionate contains not less than 97.0 percent and not more than 103.0 percent of C₂₂H₃₂O₃, calculated on the dried basis.

1 Packaging and storage

Preserve in well-closed, light-resistant containers.

USP Reference standards 〈11〉—

USP Testosterone Propionate RS

2 Identification

Change to read:

A: Spectroscopic Identification Tests 〈197〉, Infrared Spectroscopy: 197K (CN 1-May-2020) .

Change to read:

B: Spectroscopic Identification Tests 〈197〉, Ultraviolet-Visible Spectroscopy: 197U (CN 1-May-2020) —

Solution: 10 μg per mL.

Medium: alcohol.

Absorptivities at 241 nm, calculated on the dried basis, do not differ by more than 3.0%.

C: It responds to Identification test C under Testosterone Enanthate.

Melting range 〈741〉: between 118° and 123°.

Specific rotation 〈781S〉: between +83° and +90°.

Test solution: 20 mg, previously dried, per mL, in dioxane.

Loss on drying 〈731〉—Dry it in vacuum over silica gel for 4 hours: it loses not more than 0.5% of its weight.

3 Assay

Proceed with Testosterone Propionate as directed in the Assay under Testosterone Enanthate, except to use USP Testosterone

Propionate RS and otherwise substitute Testosterone Propionate throughout. Calculate the quantity, in mg, of C₂₂H₃₂O₃ in the Testosterone

Propionate taken by the formula given therein.