tert-Butyl Methyl Ether
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
C5H12O 88.15 CAS RN®: 1634-04-4.-Colorless liquid.
ASSAY: Inject an appropriate specimen into a gas chromatograph (see Chromatography (621)) equipped with a flame-ionization detector, helium being used as the carrier gas. The following conditions have been found suitable: a 0.25-mm x 30-m capillary column coated with a 1-µm layer of phase G2; the injection port temperature is maintained at 100°; the detector temperature is maintained at 300°; and the column temperature is maintained at ambient temperature and programmed to rise 10° per minute to 150°. The area of the C5H12O peak is not less than 99.8% of the total peak area. 12
REFRACTIVE INDEX (831): between 1.367 and 1.371 at 20°.

