Suspension Structured Vehicle

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Suspension Structured Vehicle

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  1. DEFINITION
  2. ADDITIONAL REQUIREMENTS

This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition

Issued and maintained by the United States Pharmacopeial Convention (USP)

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1 DEFINITION

Prepare Suspension Structured Vehicle as follows (see Pharmaceutical Compounding—Nonsterile Preparations 〈795〉).

Potassium Sorbate0.15 g
Xanthan Gum0.15 g
Citric Acid, Anhydrous0.15 g
Sucrose20 g
Purified Water, a sufficient quantity to make100 mL

Transfer the Potassium Sorbate to a suitable beaker, and dissolve in 50 mL of Purified Water. Place the beaker on an electric hot plate and stirrer, and add the Xanthan Gum into the vortex while slowly stirring. Apply minimal heat, and incorporate the Citric Acid and the Sucrose. Add a sufficient quantity of Purified Water to obtain a final volume of 100 mL, and mix.

2 ADDITIONAL REQUIREMENTS

Packaging and Storage: Package in tight, light-resistant containers. Store at room temperature, and avoid freezing.

Labeling: Label it to state that it must be well shaken before use.

Beyond-Use Date: NMT 30 days after the date on which it was compounded

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