Sodium Bitartrate
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
NaHC4H4O6 . H2O 190.08 CAS RN®: 6131-98-2.-White crystals or a crystalline powder. Soluble in cold water.
- ASSAY: Dissolve about 500 mg, accurately weighed, in 30 mL of water, add phenolphthalein TS, and titrate with 0.1 N sodium hydroxide VS: each mL of 0.1 N sodium hydroxide is equivalent to 19.01 mg of NaHC4H4O6 . H2O. Between 99% and 100.5% is found.
- INSOLUBLE MATTER (Reagent test): not more than 1 mg, from 10 g (0.01%).
- CHLORIDE (Reagent test): One g shows not more than 0.2 mg of Cl (0.02%).
- HEAVY METALS (Reagent test): Dissolve 4 g in 25 mL of water, add 2 drops of phenolphthalein TS, and then add ammonia TS, dropwise, until the solution is slightly pink. Add 4 mL of 1 N hydrochloric acid, dilute with water to 40 mL, and add 10 mL of hydrogen sulfide TS: any brown color produced is not darker than that of a control containing 0.04 mg of added Pb (0.001%).
- SULFATE (Reagent test, Method I): One g shows not more than 0.2 mg of SO4 (0.02%).
