Resorcinol Monoacetate
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
1 Identification—
A:
Fuse 3 drops with about 300 mg of phthalic anhydride and about 50 mg of zinc chloride: a small portion of the fused mixture when dissolved in 10 mL of 1 N sodium hydroxide produces an intense yellow-green fluorescence typical of fluorescein.
B:
Dissolve 0.5 mL in 3 mL of alcohol, add 3 drops of sulfuric acid, and boil: ethyl acetate, recognizable by its odor, is evolved.
Specific gravity 〈841〉
Between 1.203 and 1.207.
2 Acidity—
A solution of 10 mL of Resorcinol Monoacetate in 20 mL of benzene, when shaken with 100 mL of water, requires not more than 0.50 mL of 0.10 N sodium hydroxide for neutralization, methyl orange TS being used as the indicator.
Loss on drying 〈731〉
Dry it on a steam bath for 1 hour: it loses not more than 2.5% of its weight.
Residue on ignition 〈281〉
Not more than 0.1%.
