Pyrene
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
C16H10 202.25 CAS RN®: 129-00-0.-White to light yellow crystals.
Assay: Transfer about 9 mg, accurately weighed, to a 100-mL volumetric flask, dissolve in methanol, dilute with methanol to volume, and mix. Transfer 2.0 mL of this solution to a 100-mL volumetric flask, dilute with methanol to volume, and mix. Using a suitable spectrophotometer, 1-cm cells, and methanol as the blank, record the absorbance of the solution at the wavelength of maximum absorbance at about 238 nm. From the observed absorbance, calculate the absorptivity (see Ultraviolet-Visible Spectroscopy (857)): the absorptivity is not less than 432.9, corresponding to not less than 98% of C16H10
MELTING RANGE (741): between 149° and 153° over a 2° range.
