Propionic Anhydride
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
C6H10O3 130.14 CAS RN®: 123-62-6. - Colorless liquid. Is decomposed by water. Soluble in methanol, in alcohol, in ether, and in chloroform.
Assay: Accurately weigh about 350 mg into a tared, glass-stoppered flask containing 50 mL of dimethylformamide previously neutralized to the thymol blue endpoint with 0.1 N sodium methoxide in methanol VS. Titrate with 0.1 N sodium methoxide in methanol VS to the thymol blue endpoint. Perform a blank determination, and make any necessary correction. Each mL of 0.1 N sodium methoxide is equivalent to 13.014 mg of C6H10O3 . Not less than 97.0% is found.
Refractive Index 〈831〉: between 1.4035 and 1.4045 at 20°.
