Phthalimide

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Phthalimide

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  1. Assay
  2. MELTING RANGE (741)

This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition

Issued and maintained by the United States Pharmacopeial Convention (USP)

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C8H5NO2                       147.13 CAS RN®: 85-41-6.-White powder.

1 Assay

Mobile phase: Prepare a mixture of isooctane and methyl-tert-butyl ether (88:12).

Procedure: Inject about 20 µL into a suitable liquid chromatograph (see Chromatography (621)) equipped with a 230-nm detector and a 4.6-mm x 15-cm column that contains packing L3. The flow rate is about 2 mL per minute. The area of the C8H5NO2 peak is not less than 99% of the total peak area.

2 MELTING RANGE (741)

Between 233° and 235°, with decomposition.

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