p-Toluic Acid
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
CH3C6H4COOH 136.15 CAS RN®: 99-94-5.-White, crystalline powder. Sparingly soluble in hot water; very soluble in alcohol, in methanol, and in ether.
ASSAY: Transfer about 650 mg, accurately weighed, to a suitable container, dissolve in 125 mL of alcohol, add 25 mL of water, and mix. Titrate with 0.5 N sodium hydroxide VS, determining the endpoint potentiometrically. Perform a blank determination, and make any necessary correction. Each mL of 0.5 N sodium hydroxide is equivalent to 68.07 mg of C8H8O2: not less than 98% is found.
MELTING RANGE (741): over a range of 2° that includes 181".
