o-Xylene
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
C8H10 106.17 CAS RN®: 95-47-6.—Clear, colorless, mobile, ammable liquid. Insoluble in water; miscible with alcohol and with ether.
Assay: When examined by gas-liquid chromatography, it shows a purity of not less than 95%. The following conditions have been found suitable for assaying the substance: A 3-mm × 1.8-m stainless steel column packed with 1.75% hydrated aluminum silicate plus 5.0% diisodecyl phthalate on support S1. Helium, having a flow rate of about 27.5 mL per minute is the carrier gas, the detector temperature is about 280°, the injection port temperature is about 180°, and the column temperature is 80°. A flame-ionization detector is employed.
Refractive Index 〈831〉: between 1.5040 and 1.5060, at 20°.

