n-Butylamine
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
CH3CH2CH2CH2NH2 73.14 CAS RN®: 109-73-9.-Colorless to pale yellow, flammable liquid. Miscible with water, with alcohol, and with ether. Store it in tight containers. Specific gravity: about 0.740.
DISTILLING RANGE, Method I (721): Not less than 95% distills between 76° and 78°.
WATER DETERMINATION, Method I (921): not more than 1.0%, determined by the Titrimetric Method.
Chloride (Reagent test): One g (1.5 mL) shows not more than 0.01 mg of Cl (0.001%).
Acidic Impurities: To 50 mL add 5 drops of a saturated solution of azo violet in benzene, and titrate quickly with 0.1 N sodium methoxide VS to a deep blue endpoint, observing precautions to prevent absorption of atmospheric carbon dioxide as by use of an atmosphere of nitrogen: not more than 1.0 mL of 0.1 N sodium methoxide is required for neutralization.
