Mineral Oil Emulsion

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Mineral Oil Emulsion

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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition

Issued and maintained by the United States Pharmacopeial Convention (USP)

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1 DEFINITION

Prepare Mineral Oil Emulsion as follows.

Mineral oil500 mL
Acacia, in very fine powder125 g
Syrup100 mL
Vanillin40 mg
Alcohol60 mL
Purified Water, a sufficient quantity to make1000 mL

Mix the Mineral Oil with the Acacia in a dry mortar. Add 250 mL of Purified Water all at once, and emulsify the mixture. Add, in divided portions, triturating after each addition, a mixture of the Syrup, 50 mL of Purified Water, and Vanillin dissolved in Alcohol. Add Purified Water to bring the preparation to final volume, and mix.

The Vanillin may be replaced by NMT 1% of any other official flavoring substance or any mixture of official flavoring substances. Alcohol may be replaced with 60 mL of sweet orange peel tincture or 2 g of benzoic acid as a preservative.

2 SPECIFIC TESTS

Alcohol Determination, Method I 〈611〉: 4.0%–6.0% of C₂H₅OH

3 ADDITIONAL REQUIREMENTS

Packaging and Storage: Package in tight containers.

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