Magnesium
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
Mg 24.305 CAS RN®: 7439-95-4. - Silvery metal in ribbon form. Reacts slowly with water at room temperature. Dissolves readily in dilute acids with the liberation of hydrogen.
Assay: Transfer 1 g, accurately weighed, to a 250-mL volumetric flask, and dissolve in a mixture of 15 mL of hydrochloric acid and 85 mL of water. When solution is complete, dilute with water to volume, and mix. Pipet 25 mL of the dilution into a 400-mL beaker, dilute with water to 250 mL, add 20 mL of ammonia–ammonium chloride TS and a few mg of eriochrome black T trituration, and titrate with 0.1 M edetate disodium VS to a blue endpoint. Each mL of 0.1 M edetate disodium VS is equivalent to 2.430 mg of Mg. Not less than 99% is found.
