L-Asparagine
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
(L-2-Aminosuccinamic Acid), COOHCH(NH2)CH2CONH2·H2O 150.13 CAS RN®: 70-47-3.-Colorless crystals. One g dissolves in 50 mL of water; soluble in acids and in alkalies; insoluble in alcohol and in ether. Its neutral or alkaline solutions are levorotatory; its acid solutions are dextrorotatory.
SPECIFIC ROTATION (781): between +31° and +33°, determined in a solution in diluted hydrochloric acid containing the equivalent of 5 g (on the anhydrous basis, as determined by drying at 105° for 5 hours) in each 100 mL.
RESIDUE ON IGNITION (Reagent test): not more than 0.1%.
CHLORIDE (Reagent test): One g shows not more than 0.03 mg of Cl (0.003%).
SULFATE (Reagent test, Method I): One g shows not more than 0.05 mg of SO4 (0.005%).
HEAVY METALS (Reagent test): 0.002%.
NITROGEN DETERMINATION (461), Method II: between 18.4% and 18.8% of N is found.
