Isopropyl Salicylate
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
C6H4OHCOOCH(CH3)2 180.20-Colorless liquid.
Assay: Inject an appropriate specimen into a suitable gas chromatograph (see Chromatography (621)) equipped with a flame-ionization detector, helium being used as the carrier gas. The following conditions have been found suitable: a 2-mm x 1.8-m glass column packed with 7% phase G2 on support S1A; the injection port temperature is maintained at 250°; the detector temperature is maintained at 310°; the column temperature is maintained at 50° and programmed to rise 10° per minute to 250°. The area of the main peak is not less than 97% of the total peak area.
