Ethyl Salicylate
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
C9H10O3 166.17 CAS RN®: 118-61-6.—Colorless liquid.
Assay: Inject an appropriate specimen into a suitable gas chromatograph (see Chromatography 〈621〉) equipped with a flame-ionization detector, helium being used as the carrier gas. The following conditions have been found suitable: a 0.25-mm × 10-m capillary column coated with a 1-μm layer of methylsilicone; the injection port temperature is maintained at 240°; the detector temperature is maintained at 300°; the column temperature is maintained at 150° and programmed to rise 10° per minute to 250°. The area of the ethyl salicylate peak is not less than 99% of the total peak area.
Refractive Index〈831〉: between 1.5216 and 1.5236 at 20°.
