Diatomaceous Silica, Calcined
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
CAS RN®: 68855-54-9.-A form of silica (SiO2) consisting of fused frustules and fragments of diatoms. It is an amorphous, fine, light pink or white powder. Insoluble in water, in acids, and in dilute solutions of alkali hydroxides.
Loss on Ignition: Accurately weigh about 4 g, and ignite to constant weight: it loses not more than 10.0% of its weight,
Organic Impurities: It does not darken appreciably upon ignition.
LOSS ON DRYING (731): Dry it at 110° for 2 hours: it loses not more than 2.0% of its weight.
[NOTE-Suitable grades are "Chromosorb P" and "Chromosorb W," available from Grace, www.grace.com)

