D-Gluconic Acid, 50 Percent in Water,
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
C6H12O7 196.16 CAS RN®: 526-95-4.-Pale yellow liquid.
ASSAY: Dilute about 200 mg of the solution, accurately weighed, with 30 ml of water. Titrate with 0.1 N sodium hydroxide VS, determining the endpoint potentiometrically. Perform a blank determination and make any necessary correction. Each mL of 0.1 N sodium hydroxide is equivalent to 19.62 mg of C6H12O7, Not less than 49.0% is found.
REFRACTIVE INDEX (831): between 1.4160 and 1.4180 at 20°.
SPECIFIC ROTATION (781): between +9.9° and +11.9°, determined as is, at 20°.
