Compound Benzoin Tincture

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Compound Benzoin Tincture

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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
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1 DEFINITION

Prepare Compound Benzoin Tincture as follows.

Benzoin, in moderately coarse powder100 g
Aloe, in moderately coarse powder20 g
Storax80 g
Tolu Balsam40 g
Alcohol, a sufficient quantity to make1000 mL

Macerate the ingredients with 750 mL of Alcohol in a container that can be closed, and put in a warm place. Agitate it frequently during 3 days or until the soluble matter is dissolved. Transfer the mixture to a filter. When most of the liquid has drained away, wash the residue on the filter with a sufficient quantity of Alcohol, combining the filtrates to produce 1000 mL of Tincture, and mix.

2 OTHER COMPONENTS

ALCOHOL DETERMINATION (611), Method II: 74.0%-80.0% of alcohol (C₂H₂OH), the dilution made with methanol instead of with water, to approximately 2% alcohol

3 SPECIFIC TESTS

3.1 SPECIFIC GRAVITY (841): 0.870-0.885

3.2 LIMIT OF NONVOLATILE RESIDUE

Analysis: Evaporate 3 mL of Tincture in a suitable tared dish on a steam bath, and dry the residue at 100° for 2 h.

Acceptance criteria: The weight of the residue is 525-675 mg.

4 ADDITIONAL REQUIREMENTS

4.1 PACKAGING AND STORAGE:

Package in tight, light-resistant containers, and avoid exposure to direct sunlight and to excessive heat.

4.2 LABELING:

Label it to indicate that it is flammable.

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