Coal Tar Topical Solution
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
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Prepare Coal Tar Topical Solution as follows.
| Coal Tar | 200 g |
| Polysorbate 80 | 50 g |
Alcohol, a sufficient quantity, to make | 1000 mL |
Mix the Coal Tar with 500 g of washed sand (see under Reagents in the section Reagents, Indicators, and Solutions), and add the Polysorbate 80 and 700 mL of Alcohol. Macerate the mixture for 7 days in a closed vessel with frequent agitation. Filter, and rinse the vessel and the filter with sufficient Alcohol to make the product measure 1000 mL.
Packaging and storage-Preserve in tight containers.
ALCOHOL DETERMINATION (611): between 81.0% and 86.0% of C₂H₂OH.

