Cascara Sagrada Fluidextract

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Cascara Sagrada Fluidextract

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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition

Issued and maintained by the United States Pharmacopeial Convention (USP)

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1 DEFINITION

Prepare Cascara Sagrada Fluidextract as follows. To 1000 g of coarsely ground Cascara Sagrada add 3000 mL of boiling water, and allow to macerate in a suitable percolator for 2 h. Allow the percolation to proceed at a moderate rate, gradually adding boiling water until the drug is practically exhausted of its active principles. Evaporate the percolate on a water bath or in a vacuum still to NMT 800 mL. Cool, add 200 mL of alcohol and, if necessary, add sufficient water to make the product measure 1000 mL. Mix.

2 OTHER COMPONENTS

Alcohol Determination, Method I〈611〉: 18.0%–20.0% of C2H5OH

3 ADDITIONAL REQUIREMENTS

Packaging and Storage: Preserve in tight, light-resistant containers, and avoid exposure to direct sunlight and to excessive heat.

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