Calamine Topical Suspension
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
Prepare Calamine Topical Suspension as follows.
| Calamine | 80 g |
| Zinc oxide | 80 g |
| Glycerin | 20 mL |
| Bentonite Magma | 250 mL |
| Calcium Hydroxide Topical Solution, a sucient quantity to make | 1000 mL |
Dilute the Bentonite Magma with an equal volume of Calcium Hydroxide Topical Solution. Mix the powders intimately with the Glycerin and about 100 ml of the diluted magma, triturating until a smooth, uniform paste is formed. Gradually incorporate the remainder of the diluted magma. Finally add enough Calcium Hydroxide Topical Solution to make 1000 mL, and shake.
If a more viscous consistency in the Calamine Topical Suspension is desired, the quantity of Bentonite Magma may be increased to not more than 400 mL.
[NOTE-Shake the Calamine Topical Suspension before dispensing.]
Packaging and storage-Preserve in tight containers.
MICROBIAL ENUMERATION TESTS (61) and TESTS FOR SPECIFIED MICROORGANISMS (62) It meets the requirements of the tests for absence of Staphylococcus aureus and Pseudomonas aeruginosa.

