Calamine Topical Suspension

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Calamine Topical Suspension

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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition

Issued and maintained by the United States Pharmacopeial Convention (USP)

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Prepare Calamine Topical Suspension as follows.

Calamine80 g
Zinc oxide80 g
Glycerin20 mL
Bentonite Magma250 mL
Calcium Hydroxide Topical Solution, a sucient quantity to make1000 mL

Dilute the Bentonite Magma with an equal volume of Calcium Hydroxide Topical Solution. Mix the powders intimately with the Glycerin and about 100 ml of the diluted magma, triturating until a smooth, uniform paste is formed. Gradually incorporate the remainder of the diluted magma. Finally add enough Calcium Hydroxide Topical Solution to make 1000 mL, and shake.

If a more viscous consistency in the Calamine Topical Suspension is desired, the quantity of Bentonite Magma may be increased to not more than 400 mL.

[NOTE-Shake the Calamine Topical Suspension before dispensing.]

Packaging and storage-Preserve in tight containers.

MICROBIAL ENUMERATION TESTS (61) and TESTS FOR SPECIFIED MICROORGANISMS (62) It meets the requirements of the tests for absence of Staphylococcus aureus and Pseudomonas aeruginosa.

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