Bis(2-ethylhexyl) Maleate,
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
C20H36O4 340.50 CAS RN®: 142-16-5.-Colorless to pale yellow, clear liquid. Miscible with acetone and with alcohol, Specific gravity about 0.945.
Assay: Place about 2.5 g, accurately weighed, in a 250-mL flask, add 50.0 mL of 0.5 N alcoholic potassium hydroxide VS, and reflux for 45 minutes. Cool, add 0.5 mL of phenolphthalein TS, and titrate the excess alkali with 0.5 N hydrochloric acid VS. Perform a blank determination at the same time, using the same amount of 0.5 N alcoholic potassium hydroxide (see Residual Titrations under Titrimetry (541)). The difference, in ml, between the volumes of 0.5 N hydrochloric acid consumed in the test titration and blank titration, multiplied by 85.1, represents the quantity, in mg, of bis(2-ethylhexyl) maleate in the portion taken. Not less than 97% is found.

