Bentonite Magma
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Tóm tắt nội dung
This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
1 DEFINITION
Prepare Bentonite Magma as follows.
| Bentonite | 50 g |
| Purified Water, a sufficient quantity to make | 1000 g |
Sprinkle the Bentonite, in portions, upon 800 g of hot Purified Water, allowing each portion to become thoroughly wetted without stirring. Allow it to stand with occasional stirring for 24 h. Stir until a uniform magma is obtained, add Purified Water to make 1000 g, and mix.
The Magma may also be prepared by mechanical means such as by use of a blender, as follows. Place 500 g of Purified Water in the blender, and while the machine is running, add the Bentonite. Add Purified Water to make up to 1000 g or up to the operating capacity of the blender. Blend the mixture for 5-10 min, add Purified Water to make 1000 g, and mix.
2 SPECIFIC TESTS
MICROBIAL ENUMERATION TESTS (61) and TESTS FOR SPECIFIED MICROORGANISMS (62): It meets the requirements of the tests for absence of Escherichia coli.
3 ADDITIONAL REQUIREMENTS
PACKAGING AND STORAGE: Package in tight containers.
