Aprobarbital
If you find any inaccurate information, please let us know by providing your feedback here
This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
C10H14N2O3 210.23 CAS RN®: 77-02-1.—Fine, white crystalline powder. Slightly soluble in cold water; soluble in alcohol, in chloroform, and in ether.
Assay: Dissolve about 200 mg, previously dried at 105° for 2 hours and accurately weighed, in 20 mL of dimethylformamide in a 100-mL conical flask. Add 4 drops of thymol blue solution (1 in 200 in methanol), and titrate with 0.1 N lithium methoxide VS using a 10-mL buret, a magnetic stirrer, and a cover for the flask to protect against atmospheric carbon dioxide. Perform a blank determination, and make any necessary correction. Each mL of 0.1 N lithium methoxide is equivalent to 21.02 mg of C10H14N2O3 . Between 98.5% and 101.0% of C10H14N2O3 is found.
Melting Range〈741〉: between 140° and 143°.
