Anion-Exchange Resin, Chloromethylated Polystyrene- Divinylbenzene
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
—Strongly basic, cross-linked resin containing quaternary ammonium groups. It consists of small, moist, yellow beads having a characteristic flamine odor. It is available in the chloride form which can be converted to the hydroxide form by regeneration with sodium hydroxide solution (1 in 4). For satisfactory regeneration a contact time of about 25 minutes is required, after which it must be washed with water until neutral. Suitable for use in column chromatography.
[Note—A suitable resin is “Amberlite IRA-400,” available from Sigma-Aldrich, www.sigma-aldrich.com.]

