Acetylacetone
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
(2,4-Pentanedione; Diacetylmethane), C H O 100.12 CAS RN®: 123-54-6.—Clear, colorless to slightly yellow, flammable liquid.
Soluble in water; miscible with alcohol, with chloroform, with acetone, with ether, and with glacial acetic acid.
Assay: Not less than 98% of C H O , a suitable gas chromatograph equipped with a flame-ionization detector being used and helium being used as the carrier gas. The following conditions have been found suitable: a 3-mm × 1.83-m stainless steel column containing 10% phase G43 on support S1A; the injection port and detector temperatures are maintained at 250° and 310°, respectively; the column temperature is programmed to rise 8° per minute, from 50° to 220°.
Refractive Index〈831〉: between 1.4505 and 1.4525, at 20°.
