Acetic Acid, Diluted

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Acetic Acid, Diluted

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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition

Issued and maintained by the United States Pharmacopeial Convention (USP)

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(1 N Acetic Acid)—Dilute 60.0 mL of glacial acetic acid with water to make 1000 mL.

- Residue on Evaporation: Evaporate 50 mL on a steam bath, and dry the residue at 105° for 2 hours: the residue weighs not more than 1 mg (0.002%).

- Chloride (Reagent test): Five mL shows not more than 0.01 mg of Cl (2 ppm).

- Sulfate (Reagent test, Method I): Ten mL shows not more than 0.5 mg of SO (50 ppm).

- Heavy Metals (Reagent test): Evaporate 20 mL on a steam bath to dryness. Add to the residue 2 mL of the acid, dilute with water to 25 mL, and add 10 mL of hydrogen sulfide TS: any brown color produced is not darker than that of a control containing 0.04 mg of added Pb and 2 mL of the diluted acetic acid (2 ppm).

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