5-Methoxy-2-methyl-3-indoleacetic Acid

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5-Methoxy-2-methyl-3-indoleacetic Acid

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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition

Issued and maintained by the United States Pharmacopeial Convention (USP)

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C12H13NO3          219.24      CAS RN: 2882-15-7.—Off-white powder.

Assay: Transfer about 110 mg, accurately weighed, to a 100-mL beaker. Add 30 mL of methanol and dissolve by stirring. Add 40 mL of water, and mix. Titrate with 0.1 N sodium hydroxide VS, determining the endpoint potentiometrically. Perform a blank determination and make any necessary correction. Each mL of 0.1 N sodium hydroxide is equivalent to 21.92 mg of C12H13NO3. Not less than 98% is found.

Melting Range 〈741〉: between 161° and 168°, but the range between beginning and end of melting does not exceed 3°.

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