2,5-Dihydroxybenzoic Acid

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2,5-Dihydroxybenzoic Acid

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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition

Issued and maintained by the United States Pharmacopeial Convention (USP)

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C7H6O4 154.12 CAS RN®: 490-79-9. (ERR 1-Dec-2019) —Off-white powder. Freely soluble in alcohol yielding a clear, very pale yellow solution.

Assay: Dissolve about 75 mg, accurately weighed, in 30 mL of methanol. Slowly add 40 mL of water. Titrate with 0.1 N sodium hydroxide VS, determining the endpoint potentiometrically. Perform a blank determination, and make any necessary correction. Each mL of 0.1 N sodium hydroxide is equivalent to 15.41 mg of C7H6O4. Not less than 99% is found.

Melting Range〈741〉: about 207°, with decomposition.

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