2,2,2-Trifluoroethanol

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2,2,2-Trifluoroethanol

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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition

Issued and maintained by the United States Pharmacopeial Convention (USP)

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CF4CH2OH 100.04 CAS RN®: 75-89-8.—Colorless liquid.

Assay: Inject an appropriate specimen into a gas chromatograph (see Chromatography 〈621〉) equipped with a flame-ionization detector, helium being used as the carrier gas. The following conditions have been found suitable: a 0.25-mm × 30-m capillary column coated with a 1-μm layer of phase G2; the injection port temperature is maintained at 100°; the detector temperature is maintained at 150°; and the column temperature is maintained at 0° and programmed to rise 10° per minute to 150°. The area of the CF4CH2OH peak is not less than 99% of the total peak area.

Boiling Range: between 77° and 80°.

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