0.2 N Alcoholic Potassium Hydroxide VS
If you find any inaccurate information, please let us know by providing your feedback here
Tóm tắt nội dung
This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
Dissolve about 14 g of potassium hydroxide in 20 mL of water, and add aldehyde-free alcohol to make 1000 mL. Allow the solution to stand in a tightly stoppered bottle for 24 h. Then quickly decant the clear supernatant into a suitable, tight container. Store in tightly stoppered bottles, protected from light.
1 Standardization
See Volumetric Solutions, 1. Introduction.
See Titrimetry (541).
Standardize by one of the following procedures. [NOTE-Other standardization procedures may be used. See Volumetric Solutions. 2. Preparation and Standardization, 2.3 Standardization.]
Standardization with visual endpoint: Accurately measure 10 mL of 0.5 N hydrochloric acid VS. Dilute with 50 mL of water. add 2 drops of phenolphthalein TS, and titrate with the alcoholic potassium hydroxide solution until a permanent pale pink color is produced.
N= (mL HCI x N HCI) / (mL KOH)
Standardization with potentiometric endpoint: Accurately measure 5 mL of 0.5 N hydrochloric acid VS. Dilute with 50 ml of water, and titrate with the alcoholic potassium hydroxide solution. Determine the endpoint potentiometrically using a combined pH electrode suitable for non-aqueous titration.
N= (mL HCI x N HCI) / (mL KOH)
[NOTE-If this volumetric solution is used in a qualitative application such as pH adjustment, dissolution medium, or diluent, its standardization is not necessary.]
