0.1 N Potassium Hydroxide VS
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
Transfer 100 mL of 1 N potassium hydroxide VS to a 1000-mL volumetric flask. Dilute with carbon dioxide-free water to volume.
Standardization
See Volumetric Solutions, 1. Definitions.
See Titrimetry ⟨541⟩.
Standardize by one of the following procedures.
[Note—See Volumetric Solutions, 2. Preparation and Standardization, 2.3 Standardization.]
Standardization with visual endpoint: Add 2 drops of phenolphthalein TS to 20 mL of 0.1 N hydrochloric acid VS. Titrate with the potassium hydroxide solution until a permanent pale-pink color is produced.
N = (HCl × N HCl)/(mL KOH)
Standardization with potentiometric endpoint: Accurately measure about 10 mL of 0.1 N hydrochloric acid VS. Add about 50 mL of water. Titrate potentiometrically with the potassium hydroxide solution.
N = (HCl × N HCl)/(mL KOH)
[Note—If this volumetric solution is used in a qualitative application such as pH adjustment, dissolution medium, or diluent, its standardization is not required.]

