0.1 N Potassium Hydroxide VS

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0.1 N Potassium Hydroxide VS

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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition

Issued and maintained by the United States Pharmacopeial Convention (USP)

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Transfer 100 mL of 1 N potassium hydroxide VS to a 1000-mL volumetric flask. Dilute with carbon dioxide-free water to volume.

Standardization

See Volumetric Solutions, 1. Definitions.

See Titrimetry ⟨541⟩.

Standardize by one of the following procedures.

[Note—See Volumetric Solutions, 2. Preparation and Standardization, 2.3 Standardization.]

Standardization with visual endpoint: Add 2 drops of phenolphthalein TS to 20 mL of 0.1 N hydrochloric acid VS. Titrate with the potassium hydroxide solution until a permanent pale-pink color is produced.

N =  (HCl × N HCl)/(mL KOH)

Standardization with potentiometric endpoint: Accurately measure about 10 mL of 0.1 N hydrochloric acid VS. Add about 50 mL of water. Titrate potentiometrically with the potassium hydroxide solution.

N =  (HCl × N HCl)/(mL KOH)

[Note—If this volumetric solution is used in a qualitative application such as pH adjustment, dissolution medium, or diluent, its standardization is not required.]

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