0.1 N Methanolic Potassium Hydroxide VS
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
5.612 g in 1000 mL
Dissolve about 6.8 g of potassium hydroxide in 4 mL of water, and add methanol to make 1000 mL. Allow the solution to stand in a tightly stoppered bottle for 24 h. Then quickly decant the clear supernatant into a suitable, tight container.
Standardization: Accurately measure about 25 mL of 0.1 N hydrochloric acid VS. Dilute with 50 mL of water, add 2 drops of phenolphthalein TS, and titrate with the methanolic potassium hydroxide solution until a permanent, pale pink color is produced. [Note—Store in tightly stoppered bottles, protected from light.]
N=(mL HCl × N HCl)/(mL KOH)
[Note—If this volumetric solution is used in a qualitative application such as pH adjustment, dissolution medium, or diluent, its standardization is not required.]
