0.01 N Iodine VS

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0.01 N Iodine VS

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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition

Issued and maintained by the United States Pharmacopeial Convention (USP)

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I, 126.90

1.269 g in 1000 mL

Dissolve about 1.4 g of iodine in a solution of 3.6 g of potassium iodide in 100 mL of water, add 3 drops of hydrochloric acid, and dilute with water to 1000 mL.

Standardization: Transfer 100.0 mL of iodine solution to a 250-mL flask, add 1 mL of 1 N hydrochloric acid, swirl gently to mix, and titrate with 0.1 N sodium thiosulfate VS until the solution has a pale yellow color. Add 2 mL of starch TS, and continue titrating until the solution is colorless.

Preserve in amber-colored, glass-stoppered bottles.

[Note—If this volumetric solution is used in a qualitative application such as pH adjustment, dissolution medium, or diluent, its standardization is not required.]

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