0.001 N Silver Nitrate VS

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0.001 N Silver Nitrate VS

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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition

Issued and maintained by the United States Pharmacopeial Convention (USP)

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Transfer 1 0 mL of 0.1 N silver nitrate VS to a 1 000-mL volumetric flask. Dilute with water to volume. Otherwise, dissolve about 1 75 mg of silver nitrate in 1 000 mL of water.

Standardization

See Volumetric Solutions, 1. Introduction. See Titrimetry 〈541 〉.

Standardize by one of the following procedures. [NOTE—Other standardization procedures may be used. See Volumetric Solutions, 2. Preparation and Standardization, 2.3 Standardization.]

Standardization with visual endpoint: Transfer 0.1 0 mL of 0.1 N sodium chloride VS to a 1 50-mL beaker containing 50 mL of water, and add 50 mL of alcohol, 5 mL of acetic acid, and 0.5 mL of eosin Y TS. Stir, preferably with a magnetic stirrer, and titrate with the silver nitrate solution.

N = (mL NaCl × N NaCl)/(mL AgNO3)

Standardization with potentiometric endpoint: Transfer 0.1 0 mL of 0.1 N sodiummcLhAlogNriOde3 VS to a 1 50-mL beaker containing 50 mL of water, and add 50 mL of alcohol and 5 mL of acetic acid. Stir, preferably with a magnetic stirrer, and titrate with the silver nitrate solution using a combined silver electrode.

N = (mL NaCl × N NaCl)/(mL AgNO3)

[NOTE—If this volumetric solution is used in a qualitative application such as pH adjumsLtmAgeNnOt,3 dissolution medium, or diluent, its standardization is not required.] (USP 1 -DEC-2021 )

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