0.1 N Iodine VS
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This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition
Issued and maintained by the United States Pharmacopeial Convention (USP)
I, 126.90
12.69 g in 1000 mL
Dissolve about 14 g of iodine in a solution of 36 g of potassium iodide in 100 mL of water, add 3 drops of hydrochloric acid, and dilute with water to 1000 mL.
Standardization: Transfer 25.0 mL of the iodine solution to a 250-mL flask, dilute with water to 100 mL, add 1 mL of 1 N hydrochloric acid, swirl gently to mix, and titrate with 0.1 N sodium thiosulfate VS until the solution has a pale yellow color. Add 2 mL of starch TS and continue titrating until the solution is colorless.
Preserve in amber-colored, glass-stoppered bottles.
N = (mL Na2S2O3 x N Na2S2O3)/25
[NOTE-If this volumetric solution is used in a qualitative application such as pH adjustment, dissolution medium, or diluent, its standardization is not required.]
