0.01 N Silver Nitrate VS

This article is compiled based on the United States Pharmacopeia (USP) – 2025 Edition

Issued and maintained by the United States Pharmacopeial Convention (USP)

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Transfer 100 mL of 0.1 N silver nitrate VS to a 1000-mL volumetric flask. Dilute with water to volume. Otherwise, dissolve about 1.75 g of silver nitrate in 1000 mL of water.

1 Standardization

See Volumetric Solutions. 1. Introduction.

See Titrimetry (541).

Standardize by one of the following procedures. [NOTE-Other standardization procedures may be used. See Volumetric Solutions, 2. Preparation and Standardization, 2.3 Standardization.]

1.1 Standardization with visual endpoint

Transfer 0.50 ml. of 0.1 N sodium chloride VS to a 150-mL beaker containing 50 mL of water, and add 50 mL of alcohol, 5 mL of acetic acid, and 0.5 mL of eosin Y TS. Stir, preferably with a magnetic stirrer, and titrate with the silver nitrate solution.

                N = (mL NaCl x N NaCl)/(mL AgNO₃)

1.2 Standardization with potentiometric endpoint

Transfer 0.50 mL of 0.1 N sodium chers to a 150-ml. beaker containing 50 mL of water, and add 50 mL of alcohol, 5 mL of acetic acid. Stir, preferably with a magnetic stirrer, and titrate with the silver nitrate solution using a combined silver electrode.

                N = (mL NaCl x N NaCl)/(mL AgNO₃)

[NOTE-If this volumetric solution is used in a qualitative application such as pH adjustlemissolution medium, or diluent, its standardization is not required.] _{▲(USP 1-A00-2023)}